INTERNATIONAL EGG DONATION PROGRAM
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Join us in helping patients to build happy families. For further information please contact us directly.
Cooperation with the patient referring physician is an important part of egg donation programs. We completely reimburse physician professional efforts during the recipient preparation follow up. Join us in helping patients to build happy families.
We are pleased to introduce our comprehensive single and multiple steps egg donation programs for your patients with different convenient payment plans. Sperm washing is applied for HIV sero-discordant couples. PGS is available. Additional programs and special discounts are offered up on the physician request.
IVF program director Gulnara Makhmudova MD. PhD
4 donors oocyte single step program with an included one embryo transfer and referring physician reward for the patient endometrial preparation follow up.
6 donor oocytes two steps program with included two embryo transfers and referring physician reward for included in the program two cycles of the endometrial preparation and patient follow up.
8 donor oocytes three steps program with included three embryo transfers and referring physician reward for up to three included in program cycles of the endometrial preparation and patient follow up.
12 donor oocytes five steps program with included five embryo transfers and referring physician reward for up to five included in program cycles of the endometrial preparation and patient follow up.
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RECOMMENDED ROUTINE ENDOMETRIUM PREPARATION PROTOCOL FOR VITRIFIED OOCYTES AND EMBRYO DONATION PROGRAMS
Diagnostic hysteroscopy and ultrasound examinations are recommended on the eve of patient endometrial preparation.
There is no need in donor and recipient cycles synchronization for vitrified egg and embryo donation programs.
You can choose to follow our recommendations for routine recipient endometrial preparation protocols.
The initial daily oral estrogen dose is 6 mg (proginova or estrofem 2 mg TID) from the first day of the natural or artificial menstrual cycle. After 9-11 days an ultrasound examination is performed to adjust the estrogen dose and detect the leading follicle. If after 9-11 days the endometrial thickness is ≥ 8 mm and no leading follicle ≥ 10 mm is present, the same estrogen dose is administered till the day 13 and then the intravaginal micronized progesterone (utrogestan 200 mg TID or endomerin 100 mg TID ) is commenced. When the endometrial thickness is less than 8 mm, the estrogen dose is raised to 2 mg 4 times daily for the next 7-9 days. Then the endometrium is checked once again and if the endometrial lining is ≥ 8 mm, a progesterone support is added to the regime. In cases when the endometrium still doesn’t reach 8 mm, the progesterone support is added regardless the endometrial thickness, or the cycle is canceled based on the referring physician and patient decision. The IVF lab should be informed about the day when a progesterone support is added to perform the oocytes fertilization and plan the embryotransfer 3 days after the fertilization. Up on the patient and referring physician request the embryotransfer may be postponed to a day 5. The sperm sample should be available to the day of the oocytes fertilization. In cycles with already stored embryos the lab notifies the referring physician about the stage of the embryo freezing to plan the progesterone commencing and embryotransfer based on the development stage when embryos were vitrified.
Less than 5% of the premenopausal women will have a spontaneous ovulation with the 6 mg estrogen dose, started from the first day of menstrual cycle. There is no need in routine administration of a GnRH agonist in a previous cycle to prevent the spontaneous ovulation. In these rare cases when a dominant follicle development will be detected by an ultrasound examination after 9-11 days with a decent probability for the spontaneous ovulation, the leading follicle should be monitored and when the progesterone support has to be still delayed for several days and the follicle is close to13-14mm, GnRH antagonist (cetrorelix) 0.25 mg daily is administered to the day of the progesterone support commencing. Following this protocol, the premature luteinization or spontaneous ovulation probability is very low. To rule out this possibility, on the day before planned progesterone commencing a blood sample for serum luteinizing hormone (LH) and progesterone levels is collected. If these are raised (serum LH ≥ 13 IU/l or progesterone ≥ 15 nmol/l), luteinization of the follicle is considered to have taken place and because of the associated diminished pregnancy rates, the cycle has to be cancelled.